Gastro-intestinal haemorrhage from peptic ulcer.

Gastro-duodenal peptic ulcer perforation.

OBJECTIVES To determine the epidemiology of, and define the morbidity and mortality factors following emergency surgery for patients with perforated peptic ulcer disease in Accra, Ghana. DESIGN A retrospective and prospective hospital-based study. SETTING The general and paediatric surgical wards of the Korle-Bu Teaching Hospital. MAIN OUTCOME MEASURES Demography, the systolic BP, pulse r...

Medical aspects of gastro-intestinal haemorrhage.

Most published figures show a mortality under conservative treatment of between 5 and 10% (note reduction corresponding to the introduction of blood transfusion). Though the mortality of haemorrhage from chronic gastric ulcer is considerably higher than at other sites the most important correlation is with age. Above 50 years the death rate increases sharply, and the third factor that significa...

Surgical aspects of gastro-intestinal haemorrhage.

Acid suppression in peptic ulcer haemorrhage: a 'meta-analysis'.

BACKGROUND The use of acid-decreasing agents in the management of peptic ulcer haemorrhage continues to be controversial. Most clinical trials examining the efficacy of these drugs contain small numbers of patients, making it difficult to draw conclusions about their efficacy. METHODS We report a meta-analysis that examined the effect of these drugs in the management of peptic ulcer haemorrha...

Surgical management of idiopathic upper gastro-intestinal haemorrhage.

Of 776 patients admitted as emergency with acute upper gastro-intestinal haemorrhage, 260 were operated for uncontrollable bleeding. At surgery the cause of bleeding could not be determined in 42 (15%) cases. Vagotomy and drainage was done in 30 and gastric resection in 1 2 cases. Two patients died after gastrectomy (2/12). Follow up of 38 cases for 5 years showed good results. Two cases were l...